Double-Check Dosing of Direct Oral Anticoagulants (DOACs) in Certain Patients

July 2017

How should you dose direct oral anticoagulants (DOACs) such as Pradaxa (dabigatran) in obese, low body weight, or dialysis patients?

There's not much evidence to guide DOAC dosing in these patients...so stick with warfarin when possible.

But follow these general guidelines if a DOAC is preferred.

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Table of Contents

Diabetes Watch for Amputation Warnings With Diabetes Med Invokana
Statins Re-Evaluate Statin Use in Older Patients WithOUT CV Disease
Corticosteroids Know the Risks and Benefits of Short-Course Steroids
Inhalers Be Prepared to Switch Patients to New Fluticasone/Salmeterol Inhalers
Heart Failure Don't Jump to Newer Drugs for Systolic Heart Failure
Osteoporosis Stick With Bisphosphonates First-Line for Most Postmenopausal Women
Transdermal Patches Help Avoid Common Errors With Transdermal Patches
Anticoagulants Double-Check Dosing of Direct Oral Anticoagulants (DOACs) in Certain Patients
UTIs Compare Options for Preventing Recurrent UTIs
Parkinson's Disease Consider Xadago a Me-Too MAO-B Inhibitor for Parkinson's Disease
Musculoskeletal Sort Through Options for Treating Nocturnal Leg Cramps