Usually Treat VRE Bacteremia With Daptomycin

We're getting questions about how to treat adults with vancomycin-resistant enterococcus (VRE) bacteremia.

It's a growing problem...nearly 80% of E. faecium and 10% of E. faecalis strains in the U.S. are now resistant to vancomycin.

Daptomycin (Cubicin, etc) or linezolid (Zyvox, etc) are the primary antibiotic options. Limited evidence suggests similar efficacy...but daptomycin is often preferred for severe infections since higher doses are bacteriCIDAL, and linezolid is bacterioSTATIC.