Continue to Use Dopamine Agonists First for Restless Legs Syndrome

You'll see more interest in using pregabalin (Lyrica) for restless legs syndrome.

These patients often get a dopamine agonist (pramipexole, ropinirole, rotigotine) reduce unpleasant leg sensations and movement urges and improve sleep.

But over time, dopamine agonists can cause symptoms to worsen, occur earlier in the day, and spread to the arms, trunk, or face.

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