whether VAGINAL estrogens are safe for women taking aromatase inhibitors

May 2006

There's concern about whether VAGINAL estrogens are safe for women taking aromatase inhibitors...Arimidex, Aromasin, and Femara.

Aromatase inhibitors cause vaginal dryness and atrophy in about 20% of these women. Many are prescribed vaginal estrogen products...Premarin Vaginal Cream, Vagifem, Estring, etc.

But these could do more harm than good if too much estrogen is absorbed.

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