Don't Automatically Blame Pip/Tazo Plus Vancomycin For Declining Kidney Function

May 2016

Questions are coming up about whether the combination of piperacillin/tazobactam plus vancomycin increases nephrotoxicity.

This antibiotic combo is a workhorse for the treatment of sepsis, healthcare-acquired pneumonia, etc.

But some new evidence suggests it's linked to a higher risk of acute kidney injury...compared to vancomycin plus cefepime or meropenem.

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