how to use PPIs in patients taking clopidogrel (Plavix)

January 2011

Cardiology and GI experts now recommend a common sense approach about how to use PPIs in patients taking clopidogrel (Plavix).

Some PPIs can reduce clopidogrel's antiplatelet activity...but whether this is clinically significant is controversial.

Some observational trials suggest that patients taking a PPI with clopidogrel have a higher risk of MIs and death.

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