a potential interaction between proton pump inhibitors and clopidogrel (Plavix)

April 2008

You might hear about a potential interaction between proton pump inhibitors and clopidogrel (Plavix).

Patients commonly receive a PPI when getting clopidogrel...to decrease the risk of GI bleeding.

In vitro tests suggest that clopidogrel doesn't inhibit platelets as well in patients taking omeprazole.

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