Trimethoprim-Sulfamethoxazole is no longer effective for uncomplicated UTIs.

  There's lots of talk about the increasing resistance of E. coli to TMP-SMX (Bactrim, Septra, etc). But in many areas, E. coli is still susceptible to TMP-SMX. Nevertheless, many clinicians are automatically reaching for quinolones...even in areas with little resistance.

  Now experts are concerned about quinolones being overused for uncomplicated urinary tract infections (UTIs). In fact, quinolone resistance is on the rise in some areas.

  TMP-SMX is still preferred for uncomplicated UTIs...UNLESS local resistance is higher than 20%.

Get concise, unbiased advice for effective drug therapy, plus CE/CME

Prescriber Insights: APRN includes:

  • Cutting-edge advice about new medications and how they fit into practice
  • Unbiased, evidence-based, 100% free of financial support from the pharma industry written by your peers
  • Side-by-side comparisons of drugs by class or disease state, plus FAQs, pros/cons, and simple recommendations

Already a subscriber? Log in

Volume pricing available. Get a quote