Cenestin is better because it's natural.
Ads for Cenestin claim its estrogen formulation is plant-derived. Some women are misinterpreting these ads to mean that Cenestin is natural.
Cenestin is not natural. It's a SYNTHETIC version of nine of the conjugated HORSE estrogens in Premarin. The difference is the estrogens in Cenestin are synthesized from soy and yams...rather than pregnant mare's urine.
Women requesting "natural hormones" usually want both hormones from natural sources AND bioidentical hormones. But they can't have it both ways.