the risk of death from an overdose of venlafaxine (Effexor, Effexor XR) is higher than SSRIs

You'll hear a new warning that the risk of death from an overdose of venlafaxine (Effexor, Effexor XR) is higher than SSRIs.

There are several reasons why venlafaxine might be riskier.

Fatalities are rare with an SSRI overdose. But venlafaxine increases both serotonin and norepinephrine. Too much norepi causes high blood pressure, arrhythmias, seizures, etc.