Don’t Routinely Jump to New Antibiotics for Complicated UTIs

November 2025

New guidelines from the Infect Dis Soc of America stress stewardship around antibiotics for complicated urinary tract infections (cUTIs).

Be aware of IDSA’s new UTI definitions. Before, a cUTI was anything other than acute cystitis or pyelonephritis in nonpregnant women.

Now, simple cystitis in men is considered UNcomplicated.

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