Avoid Savaysa for A Fib if CrCl is OVER 95 mL/min

March 2015

Savaysa (sa-VAYE-sah, edoxaban) will be the fourth new oral anticoagulant (NOAC)...after Pradaxa, Xarelto, and Eliquis.

It's approved for atrial fib and venous thromboembolism (VTE).

But Savaysa has an odd twist when used for A fib. It does NOT work as well as warfarin in patients with NORMAL kidney function.

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Table of Contents

Vaccines Ask Parents to Sign a "Refusal to Vaccinate" Form
Insulin Consider Afrezza as an Alternative to Mealtime Insulin Injections
Kidney Stones Use Doxazosin for Kidney Stones if Tamsulosin Isn't Available
Women's Health Save Opioids for Severe Pain During Pregnancy
Respiratory & Allergy Tell Patients All OTC and Rx Nasal Steroids Work About the Same
Anticoagulants Avoid Savaysa for A Fib if CrCl is OVER 95 mL/min
Rosacea Consider Soolantra for Rosacea if Metronidazole Isn't Enough
Psoriasis Be Aware Otezla May Be Safer Than Methotrexate for Plaque Psoriasis
Eating Disorders Consider Vyvanse for Adults Who Binge Eat More Than 3 Days Per Week
Readmissions See Patients Within 7 to 14 Days of Discharge to Prevent Readmissions
Diabetes Use Metformin in STABLE Kidney Disease
New Drugs Save Ceftolozane/Tazobactam for Resistant E. coli or Pseudomonas
Infectious Diseases Consider Steroids for CAP Patients on the Floor