Listen for Buzz About Baxdrostat for Resistant Hypertension

You’ll hear about new Rx baxdrostat (Baxfendy), the first aldosterone synthase inhibitor for uncontrolled or resistant hypertension.

It prevents aldosterone from being made...which helps to reduce sodium and water retention. This is different from mineralocorticoid receptor antagonists (spironolactone, etc)...which block aldosterone from binding to its receptors after it’s produced.

Evidence suggests that adding once daily baxdrostat lowers systolic blood pressure by about 10 mm Hg more than placebo over 12 weeks...in patients with hypertension not controlled on multiple BP meds.